API reference
PROMETHAZINE HCl
- CAS number
- 58-33-3
- Molecular formula
- C17H21ClN2S
- Molecular weight
- 320.9 g/mol
About this molecule
Promethazine Hydrochloride is the hydrochloride salt form of promethazine, a phenothiazine derivative with antihistaminic, sedative and antiemetic properties. Promethazine hydrochloride selectively blocks peripheral H1 receptors thereby diminishing the effects of histamine on effector cells. Promethazine hydrochloride also blocks the central histaminergic receptors, thereby depressing the reticular system causing sedative and hypnotic effects. In addition, promethazine hydrochloride also has centrally acting anticholinergic properties and probably mediates nausea and vomiting by acting on the medullary chemoreceptive trigger zone.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine;hydrochloride
- InChIKey
- XXPDBLUZJRXNNZ-UHFFFAOYSA-N
- SMILES
- CC(CN1C2=CC=CC=C2SC3=CC=CC=C31)N(C)C.Cl
- PubChem CID
- 6014
Also known as
PROMETHAZINE HYDROCHLORIDE · Promethazine Hcl · Remsed · Diprasine · Fellozine · Promethacon · Promethegan · Ganphen
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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