API reference
PROPAFENONE HCl
- CAS number
- 34183-22-7
- Molecular formula
- C21H28ClNO3
- Molecular weight
- 377.9 g/mol
About this molecule
Propafenone Hydrochloride is the hydrochloride salt form of propafenone with class 1C antiarrhythmic effects. Propafenone hydrochloride stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels, thereby reducing sodium influx required for the initiation and conduction of impulses in Purkinje and myocardial cells. This agent produces a marked depression of phase 0 and prolonged effective refractory period in the atrio-ventricular nodal and His-Purkinje tissue, resulting in a profound decrease in excitability, conduction velocity and automaticity, thereby counteracting atrial and ventricular arrythmias.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenylpropan-1-one;hydrochloride
- InChIKey
- XWIHRGFIPXWGEF-UHFFFAOYSA-N
- SMILES
- CCCNCC(COC1=CC=CC=C1C(=O)CCC2=CC=CC=C2)O.Cl
- PubChem CID
- 36708
Also known as
PROPAFENONE HYDROCHLORIDE · Propafenone HCl · Rythmol SR · Baxarytmon · Propafenon hydrochlorid · Hydrochloride, Propafenone · 251-867-9 · Rythmol
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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