API reference

Ramelteon

CAS number
196597-26-9
Molecular formula
C16H21NO2
Molecular weight
259.34 g/mol
Ramelteon — 2D structure
2D structure (PubChem)

About this molecule

Ramelteon is a synthetic melatonin analogue with hypnotic and circadian rhythm-modulating activities. Ramelteon binds to and activates melatonin receptors 1 and 2 in the suprachiasmatic nucleus (SCN) of the brain, thereby promoting the onset of sleep. Unlike the nonbenzodiazepine sedative hypnotics zolpidem and zaleplon, this agent does not activate GABA receptors and, so, produces no GABA receptor-mediated anxiolytic, myorelaxant, and amnesic effects.

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
N-[2-[(8S)-2,6,7,8-tetrahydro-1H-cyclopenta[e][1]benzofuran-8-yl]ethyl]propanamide
InChIKey
YLXDSYKOBKBWJQ-LBPRGKRZSA-N
SMILES
CCC(=O)NCC[C@@H]1CCC2=C1C3=C(C=C2)OCC3
PubChem CID
208902

Also known as

Ramelteon · Rozerem · TAK-375 · ramelteonum · TAK375 · N05CH02 · Rozerem (TN) · Ramelteon (JAN/USAN/INN)

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