API reference
Ranolazine
- CAS number
- 95635-55-5
- Molecular formula
- C24H33N3O4
- Molecular weight
- 427.5 g/mol
About this molecule
Ranolazine is an orally available, piperazine derivative with anti-anginal and potential antineoplastic activities. Ranolazine's mechanism of action for its anti-ischemic effects has yet to be fully elucidated but may involve the alteration of the trans-cellular late sodium current in the ischemic myocyte. By preventing the rise of intracellular sodium levels, ranolazine may affect the transport activity of sodium-dependent calcium channels and prevent the calcium overload during myocardial ischemia, thereby preventing cellular injury. Ranolazine's potential antineoplastic effect may depend on its inhibitory effect on fatty acid oxidation, which may sensitize tumor cells to apoptosis and decrease tumor cell proliferation; fatty acid oxidation provides energy and promotes tumor cell proliferation and survival.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- N-(2,6-dimethylphenyl)-2-[4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl]acetamide
- InChIKey
- XKLMZUWKNUAPSZ-UHFFFAOYSA-N
- SMILES
- CC1=C(C(=CC=C1)C)NC(=O)CN2CCN(CC2)CC(COC3=CC=CC=C3OC)O
- Other CAS numbers recorded
- 142387-99-3 · 1080496-58-7
- PubChem CID
- 56959
Also known as
Ranexa · CVT-303 · RAN D · Ran4 · renolazine · (+-)-Ranolazine · ASPRUZYO · Ranolazina
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
Tell us the grade, the quantity and the market.
Send the molecule or ingredient, the specification and the destination. We reply from Tehran with the questions, the documents and the next step.