API reference
Regorafenib
- CAS number
- 755037-03-7
- Molecular formula
- C21H15ClF4N4O3
- Molecular weight
- 482.8 g/mol
About this molecule
Regorafenib is a pyridinecarboxamide obtained by condensation of 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]pyridine-2-carboxylic acid with methylamine. Used for for the treatment of metastatic colorectal cancer in patients who have previously received chemotherapy, anti-EGFR or anti-VEGF therapy. It has a role as an antineoplastic agent, a tyrosine kinase inhibitor and a hepatotoxic agent. It is a member of phenylureas, a pyridinecarboxamide, an aromatic ether, a member of monochlorobenzenes, a member of (trifluoromethyl)benzenes and a member of monofluorobenzenes.
Source: ChEBI, via PubChem.
Identifiers
- IUPAC name
- 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide
- InChIKey
- FNHKPVJBJVTLMP-UHFFFAOYSA-N
- SMILES
- CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F
- PubChem CID
- 11167602
Also known as
Regorafenib · Stivarga · Regorafenibum · REGORAFENIB ANHYDROUS · L01XE21 · C21H15ClF4N4O3 · Stivarga (TN) · Regorafenib (Standard)
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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