API reference
Remdesivir
- CAS number
- 1809249-37-3
- Molecular formula
- C27H35N6O8P
- Molecular weight
- 602.6 g/mol
About this molecule
Remdesivir is a carboxylic ester resulting from the formal condensation of the carboxy group of N-[(S)-{[(2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(phenoxy)phosphoryl]-L-alanine with the hydroxy group of 2-ethylbutan-1-ol. A broad-spectrum antiviral prodrug with potent in vitro antiviral activity against a diverse panel of RNA viruses such as Ebola virus, MERS-CoV and SARS-CoV. It is currently in Phase III clinical trials for the treatment of Covid-19 in adults. It has a role as an anticoronaviral agent, an antiviral drug and a prodrug. It is a nitrile, a phosphoramidate ester, a carboxylic ester, an aromatic amine, a C-nucleoside and a pyrrolotriazine. It is functionally related to a GS-441524.
Source: ChEBI, via PubChem.
Identifiers
- IUPAC name
- 2-ethylbutyl (2S)-2-[[[(2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxyoxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate
- InChIKey
- RWWYLEGWBNMMLJ-YSOARWBDSA-N
- SMILES
- CCC(CC)COC(=O)[C@H](C)N[P@](=O)(OC[C@@H]1[C@H]([C@H]([C@](O1)(C#N)C2=CC=C3N2N=CN=C3N)O)O)OC4=CC=CC=C4
- PubChem CID
- 121304016
Also known as
Remdesivir · Veklury · remdesivirum · SARS-CoV-2 antiviral agents: remdesivir · Veklury (TN) · Remdesivir (Standard) · Remdesivir (JAN/USAN)
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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