API reference

Revefenacin

CAS number
864750-70-9
Molecular formula
C35H43N5O4
Molecular weight
597.7 g/mol
Revefenacin — 2D structure
2D structure (PubChem)

About this molecule

Revefenacin is a novel biphenyl carbamate tertiary amine agent that belongs to the family of the long-acting muscarinic antagonists (LAMA). The labile primary amide in the structure produces a "soft-drug" site that allows rapid systemic clearance and minimizing of the systemically mediated adverse reactions. The LAMA group falls into a parent category known as long-acting inhaled bronchodilators and this type of agents are recommended as a maintenance therapy for chronic obstructive pulmonary disease (COPD). From the LAMA group, revefenacin is the first once-daily nebulized LAMA treatment. It was developed by Theravance Biopharma and FDA approved on November 9, 2018.

Source: DrugBank, via PubChem.

Identifiers

IUPAC name
[1-[2-[[4-[(4-carbamoylpiperidin-1-yl)methyl]benzoyl]-methylamino]ethyl]piperidin-4-yl] N-(2-phenylphenyl)carbamate
InChIKey
FYDWDCIFZSGNBU-UHFFFAOYSA-N
SMILES
CN(CCN1CCC(CC1)OC(=O)NC2=CC=CC=C2C3=CC=CC=C3)C(=O)C4=CC=C(C=C4)CN5CCC(CC5)C(=O)N
Other CAS numbers recorded
1211931-83-7
PubChem CID
11753673

Also known as

Revefenacin · Yupelri · revefenacina · revefenacine · revefenacinum · R03BB08 · Yupelri (TN) · Revefenacin (Standard)

Related entries in the range

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