API reference

Ribavirin

CAS number
36791-04-5
Molecular formula
C8H12N4O5
Molecular weight
244.2 g/mol
Ribavirin — 2D structure
2D structure (PubChem)

About this molecule

Ribavirin is a 1-ribosyltriazole that is the 1-ribofuranosyl derivative of 1,2,4-triazole-3-carboxamide. A synthetic guanosine analogue, it is an inhibitor of HCV polymerase and possesses a broad spectrum of activity against DNA and RNA viruses. It has a role as an anticoronaviral agent, an antiviral agent, an antimetabolite, an antiinfective agent and an EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor. It is a primary carboxamide, a monocarboxylic acid amide, an aromatic amide and a 1-ribosyltriazole. It is functionally related to a 1,2,4-triazole-3-carboxamide.

Source: ChEBI, via PubChem.

Identifiers

IUPAC name
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide
InChIKey
IWUCXVSUMQZMFG-AFCXAGJDSA-N
SMILES
C1=NC(=NN1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)C(=O)N
Other CAS numbers recorded
66510-90-5 · 252269-50-4
PubChem CID
37542

Also known as

ribavirin · Tribavirin · Rebetol · Virazole · Copegus · Ribamidil · Ribavirine · Viramid

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