API reference
Riluzole
- CAS number
- 1744-22-5
- Molecular formula
- C8H5F3N2OS
- Molecular weight
- 234.2 g/mol
About this molecule
Riluzole is a benzothiazole derivative with neuroprotective and potential anti-depressant and anxiolytic activities. While the mechanism of action of riluzole is unknown, its pharmacological activities in motor neurons include the following, some of which may be related to its effect: 1) an inhibitory effect on glutamate release, 2) inactivation of voltage-dependent sodium channels, and 3) interference with intracellular events that follow transmitter binding at excitatory amino acid receptors. In animal models, this agent has been shown to exhibit myorelaxant and sedative activities, apparently due to the blockade of glutamatergic neurotransmission.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 6-(trifluoromethoxy)-1,3-benzothiazol-2-amine
- InChIKey
- FTALBRSUTCGOEG-UHFFFAOYSA-N
- SMILES
- C1=CC2=C(C=C1OC(F)(F)F)SC(=N2)N
- PubChem CID
- 5070
Also known as
riluzole · Rilutek · 2-Amino-6-(trifluoromethoxy)benzothiazole · 6-(trifluoromethoxy)-1,3-benzothiazol-2-amine · Riluzol · Riluzolum · 2-Benzothiazolamine, 6-(trifluoromethoxy)- · Tiglutik
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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