API reference
Rizatriptan benzoate
- CAS number
- 145202-66-0
- Molecular formula
- C22H25N5O2
- Molecular weight
- 391.5 g/mol
About this molecule
Rizatriptan Benzoate is the benzoate salt form of rizatriptan, a member of the triptan class agents with anti-migraine property. Rizatriptan benzoate selectively binds to and activates serotonin (5-HT) 1B receptors expressed in intracranial arteries, and to 5-HT 1D receptors located on peripheral trigeminal sensory nerve terminals in the meninges and central terminals in brain stem sensory nuclei. Receptor binding results in constriction of cranial vessels and inhibition of nociceptive transmission, thereby providing relief of migraine headaches. Rizatriptan benzoate may also relief migraine headaches by inhibition of pro-inflammatory neuropeptide release.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- benzoic acid;N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethanamine
- InChIKey
- JPRXYLQNJJVCMZ-UHFFFAOYSA-N
- SMILES
- CN(C)CCC1=CNC2=C1C=C(C=C2)CN3C=NC=N3.C1=CC=C(C=C1)C(=O)O
- PubChem CID
- 77997
Also known as
Rizatriptan benzoate · Maxalt-MLT · RIZAFILM · L 705,126 · L-705,126 · SYMBRAVO COMPONENT RIZATRIPTAN BENZOATE · Rizatriptan Benzoate ODT · 604-465-6
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