API reference
Rosiglitazone maleate
- CAS number
- 155141-29-0
- Molecular formula
- C22H23N3O7S
- Molecular weight
- 473.5 g/mol
About this molecule
Rosiglitazone Maleate is the maleate salt of rosiglitazone, an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity. Rosiglitazone activates peroxisome proliferator-activated receptor gamma (PPAR-gamma), a ligand-activated transcription factor, thereby inducing cell differentiation and inhibiting cell growth and angiogenesis. This agent also modulates the transcription of insulin-responsive genes, inhibits macrophage and monocyte activation, and stimulates adipocyte differentiation.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- (Z)-but-2-enedioic acid;5-[[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
- InChIKey
- SUFUKZSWUHZXAV-BTJKTKAUSA-N
- SMILES
- CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3.C(=C\C(=O)O)\C(=O)O
- Other CAS numbers recorded
- 1217260-35-9
- PubChem CID
- 5281055
Also known as
Rosiglitazone maleate · Rosiglitzazone maleate · Avandia · Nyracta · Rosiglitazone XR · Venvia · Avandia (TN) · Rosiglitazone (maleate)
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