API reference
Rosuvastatin calcium
- CAS number
- 147098-20-2
- Molecular formula
- C44H54CaF2N6O12S2
- Molecular weight
- 1,001.1 g/mol
About this molecule
Rosuvastatin Calcium is the calcium salt form of rosuvastatin, a statin with antilipidemic activity. Rosuvastatin selectively and competitively binds to and inhibits hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, the enzyme which catalyzes the conversion of HMG-CoA to mevalonate, a precursor of cholesterol. This leads to a decrease in hepatic cholesterol levels and increase in uptake of LDL cholesterol.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- calcium bis((E,3R,5S)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate)
- InChIKey
- LALFOYNTGMUKGG-BGRFNVSISA-L
- SMILES
- CC(C1=NC(=NC(=C1/C=C/[C@@H](O)C[C@@H](O)CC(=O)[O-])C2=CC=C(C=C2)F)N(S(=O)(=O)C)C)C.CC(C1=NC(=NC(=C1/C=C/[C@@H](O)C[C@@H](O)CC(=O)[O-])C2=CC=C(C=C2)F)N(S(=O)(=O)C)C)C.[Ca+2]
- PubChem CID
- 5282455
Also known as
Rosuvastatin calcium · Crestor · Rosuvastatin hemicalcium · Rosuvastatin Calcium Salt · Fortius · Rostar · Suvikan · Rozavel
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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