API reference
Sitagliptin
- CAS number
- 486460-32-6
- Molecular formula
- C16H15F6N5O
- Molecular weight
- 407.31 g/mol
About this molecule
Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus. The effect of this medication leads to glucose dependent increases in insulin and decreases in glucagon to improve control of blood sugar. Sitagliptin was granted FDA approval on October 16, 2006.
Source: DrugBank, via PubChem.
Identifiers
- IUPAC name
- (3R)-3-amino-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one
- InChIKey
- MFFMDFFZMYYVKS-SECBINFHSA-N
- SMILES
- C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N
- Other CAS numbers recorded
- 790712-60-6
- PubChem CID
- 4369359
Also known as
Sitagliptin · Januvia · Zituvio · sitagliptina · sitagliptine · sitagliptinum · LEZ763 · LEZ-763
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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