API reference

SOTALOL HCl

CAS number
959-24-0
Molecular formula
C12H21ClN2O3S
Molecular weight
308.83 g/mol
SOTALOL HCl — 2D structure
2D structure (PubChem)

About this molecule

Sotalol Hydrochloride is the hydrochloride salt form of sotalol, an ethanolamine derivative with Class III antiarrhythmic and antihypertensive properties. Sotalol hydrochloride is a nonselective beta-adrenergic receptor and potassium channel antagonist. In the heart, this agent inhibits chronotropic and inotropic effects thereby slowing the heart rate and decreasing myocardial contractility. This agent also reduces sinus rate, slows conduction in the atria and in the atrioventricular (AV) node and increases the functional refractory period of the AV node. In the lungs, sotalol inhibits vasodilation and bronchodilation. In addition, this agent inhibits renin release.

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
N-[4-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenyl]methanesulfonamide;hydrochloride
InChIKey
VIDRYROWYFWGSY-UHFFFAOYSA-N
SMILES
CC(C)NCC(C1=CC=C(C=C1)NS(=O)(=O)C)O.Cl
PubChem CID
66245

Also known as

Sotalol hydrochloride · Sotalol HCL · Betapace · Betapace AF · Sotacor · Sotalex · Sorine · Sotylize

Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.

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