API reference
Sulbactam
- CAS number
- 68373-14-8
- Molecular formula
- C8H11NO5S
- Molecular weight
- 233.24 g/mol
About this molecule
Sulbactam is a semi-synthetic beta-lactamase inhibitor. The beta-lactam ring of sulbactam irreversibly binds to beta-lactamase at or near its active site, thereby blocking enzyme activity and preventing metabolism of other beta-lactam antibiotics by the enzyme. Combining this agent with a beta-lactamase susceptible antibiotic, such as penicillins or a cephalosporin, to treat infections caused by beta-lactamase producing organisms, results in a decreased turnover rate of the beta-lactamase sensitive antibiotic and enhances its antibacterial activity.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- (2S,5R)-3,3-dimethyl-4,4,7-trioxo-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
- InChIKey
- FKENQMMABCRJMK-RITPCOANSA-N
- SMILES
- CC1([C@@H](N2[C@H](S1(=O)=O)CC2=O)C(=O)O)C
- PubChem CID
- 130313
Also known as
SULBACTAM · Sulbactamum · Betamaze · Penicillanic Acid Sulfone · penicillanic acid 1,1-dioxide · J01CG01 · 2,2-dimethyl-1,1-dioxidopenam-3alpha-carboxylic acid · Sulfone, Penicillanic Acid
Related entries in the range
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