API reference
Sulfamethoxazole
- CAS number
- 723-46-6
- Molecular formula
- C10H11N3O3S
- Molecular weight
- 253.28 g/mol
About this molecule
Sulfamethoxazole is a bacteriostatic sulfonamide antibiotic that interferes with folic acid synthesis in susceptible bacteria. It is generally given in combination with [trimethoprim], which inhibits a sequential step in bacterial folic acid synthesis - these agents work synergistically to block two consecutive steps in the biosynthesis of nucleic acids and proteins which are necessary for bacterial growth and division, and using them in conjunction helps to slow the development of bacterial resistance. In this combination, sulfamethoxazole is useful for the treatment of a variety of bacterial infections, including those of the urinary, respiratory, and gastrointestinal tracts.
Source: DrugBank, via PubChem.
Identifiers
- IUPAC name
- 4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide
- InChIKey
- JLKIGFTWXXRPMT-UHFFFAOYSA-N
- SMILES
- CC1=CC(=NO1)NS(=O)(=O)C2=CC=C(C=C2)N
- Other CAS numbers recorded
- 144930-01-8
- PubChem CID
- 5329
Also known as
sulfamethoxazole · Gantanol · Sulphamethoxazole · Sulfisomezole · Sulfamethoxazol · 4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide · Radonil · Sinomin
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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