API reference
Sumatriptan
- CAS number
- 103628-46-2
- Molecular formula
- C14H21N3O2S
- Molecular weight
- 295.4 g/mol
About this molecule
Sumatriptan is a sulfonamide triptan with vasoconstrictor activity. Sumatriptan selectively binds to and activates serotonin 5-HT1D receptors in the central nervous system (CNS), thereby constricting cerebral blood vessels. This may lead to a relief in pain from vascular headaches. Sumatriptan may also relieve vascular headaches by decreasing the release of vasoactive neuropeptides from perivascular trigeminal axons in the dura mater during a migraine, by reducing extravasation of plasma proteins, and by decreasing the release of other mediators of inflammation from the trigeminal nerve.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 1-[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]-N-methylmethanesulfonamide
- InChIKey
- KQKPFRSPSRPDEB-UHFFFAOYSA-N
- SMILES
- CNS(=O)(=O)CC1=CC2=C(C=C1)NC=C2CCN(C)C
- PubChem CID
- 5358
Also known as
sumatriptan · Imitrex · Sumatran · Sumax · Imigran · Sumatriptanum · Imigran Recovery · TOSYMRA
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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