API reference

Tafluprost

CAS number
209860-87-7
Molecular formula
C25H34F2O5
Molecular weight
452.5 g/mol
Tafluprost — 2D structure
2D structure (PubChem)

About this molecule

Tafluprost is a prostaglandin Falpha that is prostaglandin F2alpha in which the carboxylic acid function has been converted to the corresponding isopropyl ester and the 3-hydroxy-1-octenyl side-chain is substituted by 3,3-difluoro-4-phenoxybut-1-enyl. Used for treatment of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension. It has a role as a prostaglandin receptor agonist. It is an isopropyl ester, a prostaglandins Falpha and an organofluorine compound. It is functionally related to a prostaglandin F2alpha.

Source: ChEBI, via PubChem.

Identifiers

IUPAC name
propan-2-yl (Z)-7-[(1R,2R,3R,5S)-2-[(E)-3,3-difluoro-4-phenoxybut-1-enyl]-3,5-dihydroxycyclopentyl]hept-5-enoate
InChIKey
WSNODXPBBALQOF-VEJSHDCNSA-N
SMILES
CC(C)OC(=O)CCC/C=C\C[C@H]1[C@H](C[C@H]([C@@H]1/C=C/C(COC2=CC=CC=C2)(F)F)O)O
PubChem CID
9868491

Also known as

Tafluprost · AFP-168 · Taflotan · Zioptan · Saflutan · tafluprostum · tafluprost opthalmic · Tafluprost Ophthalmic

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