API reference
Tazobactam
- CAS number
- 89786-04-9
- Molecular formula
- C10H12N4O5S
- Molecular weight
- 300.29 g/mol
About this molecule
Tazobactam is an antibiotic of the beta-lactamase inhibitor class that prevents the breakdown of other antibiotics by beta-lactamase enzyme producing organisms. It is combined with [Piperacillin] and [Ceftolozane] for the treatment of a variety of bacterial infections. Piperacillin-tazobactam was initially approved by the FDA in 1994, and ceftolozane-tazobactam was approved by the FDA in 2014, providing wider antibacterial coverage for gram-negative infections. In June 2019, ceftolozane-tazobactam was approved by the FDA for treating hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia, which are significant causes of morbidity and mortality in hospitalized patients.
Source: DrugBank, via PubChem.
Identifiers
- IUPAC name
- (2S,3S,5R)-3-methyl-4,4,7-trioxo-3-(triazol-1-ylmethyl)-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
- InChIKey
- LPQZKKCYTLCDGQ-WEDXCCLWSA-N
- SMILES
- C[C@@]1([C@@H](N2[C@H](S1(=O)=O)CC2=O)C(=O)O)CN3C=CN=N3
- Other CAS numbers recorded
- 1246733-29-8
- PubChem CID
- 123630
Also known as
Tazobactam · Tazobactamum · YTR-830H · CL 298,741 · CXA201 · YTR830 · J01CG02 · YTR-830
Related entries in the range
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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