API reference
Telmisartan
- CAS number
- 144701-48-4
- Molecular formula
- C33H30N4O2
- Molecular weight
- 514.6 g/mol
About this molecule
Telmisartan is a benzimidazole derivative and a non-peptide angiotensin II receptor antagonist with antihypertensive property. Telmisartan selectively antagonizes angiotensin II binding to the AT1 subtype receptor, located in vascular smooth muscle and adrenal gland. The antagonism results in vasodilation and inhibits the angiotensin II-mediated aldosterone production, which in turn leading to a decrease in sodium and water as well as an increase in potassium excretion leading to a subsequent reduction in blood pressure.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 2-[4-[[4-methyl-6-(1-methylbenzimidazol-2-yl)-2-propylbenzimidazol-1-yl]methyl]phenyl]benzoic acid
- InChIKey
- RMMXLENWKUUMAY-UHFFFAOYSA-N
- SMILES
- CCCC1=NC2=C(N1CC3=CC=C(C=C3)C4=CC=CC=C4C(=O)O)C=C(C=C2C)C5=NC6=CC=CC=C6N5C
- PubChem CID
- 65999
Also known as
Telmisartan · Micardis · Pritor · Kinzalmono · Semintra · BIBR 277 · tolura · BIBR-277
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