API reference

Tenofovir alafenamide fumarate

CAS number
1392275-56-7
Molecular formula
C46H62N12O14P2
Molecular weight
1,069 g/mol
Tenofovir alafenamide fumarate — 2D structure
2D structure (PubChem)

About this molecule

Tenofovir alafenamide fumarate is a fumarate salt prepared from tenofovir alafenamide by reaction of one molecule of fumaric acid for every two molecules of tenofovir alafenamide. A prodrug for tenofovir, it is used in combination therapy for the treatment of HIV-1 infection. It has a role as an antiviral drug, a prodrug and a HIV-1 reverse transcriptase inhibitor. It contains a tenofovir alafenamide(1+).

Source: ChEBI, via PubChem.

Identifiers

IUPAC name
(E)-but-2-enedioic acid;bis(propan-2-yl (2S)-2-[[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-phenoxyphosphoryl]amino]propanoate)
InChIKey
SVUJNSGGPUCLQZ-FQQAACOVSA-N
SMILES
C[C@H](CN1C=NC2=C(N=CN=C21)N)OC[P@@](=O)(N[C@@H](C)C(=O)OC(C)C)OC3=CC=CC=C3.C[C@H](CN1C=NC2=C(N=CN=C21)N)OC[P@@](=O)(N[C@@H](C)C(=O)OC(C)C)OC3=CC=CC=C3.C(=C/C(=O)O)\C(=O)O
PubChem CID
71492247

Also known as

Tenofovir Alafenamide fumarate · tenofovir alafenamide hemifumarate · TENOFOVIR ALAFENAMIDE FUMARATE (2:1) · TAF · DESCOVY COMPONENT TENOFOVIR ALAFENAMIDE FUMARATE · ODEFSEY COMPONENT TENOFOVIR ALAFENAMIDE FUMARATE · SYMTUZA COMPONENT TENOFOVIR ALAFENAMIDE FUMARATE · BIKTARVY COMPONENT TENOFOVIR ALAFENAMIDE FUMARATE

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