API reference
Tioconazole
- CAS number
- 65899-73-2
- Molecular formula
- C16H13Cl3N2OS
- Molecular weight
- 387.7 g/mol
About this molecule
Tioconazole is an imidazole antifungal used to treat fungal and yeast infections. Topical formulations are used for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus". Tioconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the yeast membrane. In this way, tioconazole inhibits ergosterol synthesis, resulting in increased cellular permeability. In addition to being an antifungal, tioconazole also has antibacterial effects on certain Gram-positive cocci bacteria.
Source: DrugBank, via PubChem.
Identifiers
- IUPAC name
- 1-[2-[(2-chlorothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole
- InChIKey
- QXHHHPZILQDDPS-UHFFFAOYSA-N
- SMILES
- C1=CC(=C(C=C1Cl)Cl)C(CN2C=CN=C2)OCC3=C(SC=C3)Cl
- PubChem CID
- 5482
Also known as
tioconazole · Vagistat · Trosyd · Trosyl · Vagistat-1 · Tioconazol · Tioconazolum · (+-)-Tioconazole
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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