API reference
TIROFIBAN HCl
- CAS number
- 142373-60-2
- Molecular formula
- C22H37ClN2O5S
- Molecular weight
- 477.1 g/mol
About this molecule
Tirofiban Hydrochloride is the hydrochloride salt form of tirofiban, a non-peptide tyrosine derivative with anticoagulant property. Tirofiban antagonizes fibrinogen binding to the platelet cell surface receptor, glycoprotein (GP) IIb/IIIA complex, one of the two purinergic receptors activated by ADP. The antagonism prevents adenylyl cyclase activation, which mediated via GP IIb/IIIa receptor complex, and results in decreased levels of cAMP and thereby interferes with platelet membrane function and subsequent platelet-platelet interaction, release of platelet granule constituents and prolongation of bleeding time.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- (2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-ylbutoxy)phenyl]propanoic acid;hydrochloride
- InChIKey
- KPKFFYOMPGOQRP-BOXHHOBZSA-N
- SMILES
- CCCCS(=O)(=O)N[C@@H](CC1=CC=C(C=C1)OCCCCC2CCNCC2)C(=O)O.Cl
- PubChem CID
- 64781
Also known as
Tirofiban hydrochloride anhydrous · TIROFIBAN HYDROCHLORIDE · Tirofiban HCl · Aggrastat · Tirofiban (hydrochloride) · C22H37ClN2O5S
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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