API reference
TIZANIDINE HCl
- CAS number
- 64461-82-1
- Molecular formula
- C9H9Cl2N5S
- Molecular weight
- 290.17 g/mol
About this molecule
Tizanidine Hydrochloride is the hydrochloride salt form of tizanidine, an imidazoline derivative structurally similar to clonidine and an adrenergic agonist with muscle relaxant property. Tizanidine stimulates alpha-2 adrenergic receptors in the central nervous system, thereby inhibiting presynaptic release of norepinephrine and increasing the inhibitory effect on alpha motor neurons and motor reflexes. Tizanidine exerts some activity at the postsynaptic excitatory amino acid receptors and imidazoline receptors which may contribute to the overall reduction in facilitation of spinal motor neurons. Overall, tizanidine hydrochloride causes muscle relaxation, reduces spasticity and antinociceptive effects.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine;hydrochloride
- InChIKey
- ZWUKMNZJRDGCTQ-UHFFFAOYSA-N
- SMILES
- C1CN=C(N1)NC2=C(C=CC3=NSN=C32)Cl.Cl
- Other CAS numbers recorded
- 74113-36-3
- PubChem CID
- 114869
Also known as
Tizanidine hydrochloride · Tizanidine Hcl · DS 103-282 · ONTRALFY · Tizanidine (as hydrochloride) · AN021 · Sirdalud MR · tizanidine monohydrochloride
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
Tell us the grade, the quantity and the market.
Send the molecule or ingredient, the specification and the destination. We reply from Tehran with the questions, the documents and the next step.