API reference
Tretinoin
- CAS number
- 302-79-4
- Molecular formula
- C20H28O2
- Molecular weight
- 300.4 g/mol
About this molecule
Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of [vitamin A] (retinol). It is an oxidation product in the physiological pathway of vitamin A metabolism. In human circulation, tretinoin is normally found at very low concentrations, approximately 4 to 14 nmol/L. Tretinoin exhibits anti-inflammatory, antineoplastic, antioxidant, and free radical-scavenging activities. It has been used in dermatology for many years to treat various skin conditions ranging from acne to wrinkles and activates nuclear receptors to regulate epithelial cell growth and differentiation. Tretinoin is given orally to treat acute promyelocytic leukemia and topically to treat skin conditions such as acne.
Source: DrugBank, via PubChem.
Identifiers
- IUPAC name
- (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid
- InChIKey
- SHGAZHPCJJPHSC-YCNIQYBTSA-N
- SMILES
- CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/C(=O)O)/C)/C
- Other CAS numbers recorded
- 97950-17-9
- PubChem CID
- 444795
Also known as
Retinoic acid · tretinoin · all-trans-Retinoic acid · Vitamin A acid · trans-Retinoic acid · ATRA · Aberel · Eudyna
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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