API reference

Triamcinolone acetonide

CAS number
76-25-5
Molecular formula
C24H31FO6
Molecular weight
434.5 g/mol
Triamcinolone acetonide — 2D structure
2D structure (PubChem)

About this molecule

Triamcinolone Acetonide is the acetonide salt form of triamcinolone, a synthetic glucocorticosteroid with immunosuppressive and anti-inflammatory activity. Triamcinolone acetonide binds to specific cytosolic glucocorticoid receptors and subsequently interacts with glucocorticoid receptor response element on DNA and alters gene expression. This results in an induction of the synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are accomplished.

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
(1S,2S,4R,8S,9S,11S,12R,13S)-12-fluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one
InChIKey
YNDXUCZADRHECN-JNQJZLCISA-N
SMILES
C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1C[C@@H]4[C@]2(OC(O4)(C)C)C(=O)CO)CCC5=CC(=O)C=C[C@@]53C)F)O
PubChem CID
6436

Also known as

TRIAMCINOLONE ACETONIDE · Azmacort · Nasacort · Vetalog · Tricinolon · Solodelf · Kenacort-A · Aristogel

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