API reference
Triamterene
- CAS number
- 396-01-0
- Molecular formula
- C12H11N7
- Molecular weight
- 253.26 g/mol
About this molecule
Triamterene is a pteridine derivative with potassium-sparing diuretic property. Triamterene blocks the sodium-potassium exchange pump (Na-K-ATPase) in the luminal membrane of principal cells in the late distal tubule, cortical collecting tubule and collecting duct in the kidney. This reversible inhibition of the electrogenic sodium transport decreases the lumen-negative transepithelial potential difference and thus reduces the driving force for K+ movement into the tubular lumen resulting in the inhibition of sodium reabsorption in exchange for K+ and H+.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 6-phenylpteridine-2,4,7-triamine
- InChIKey
- FNYLWPVRPXGIIP-UHFFFAOYSA-N
- SMILES
- C1=CC=C(C=C1)C2=NC3=C(N=C(N=C3N=C2N)N)N
- PubChem CID
- 5546
Also known as
triamterene · 6-phenylpteridine-2,4,7-triamine · 2,4,7-Triamino-6-phenylpteridine · Dyrenium · Dytac · Pterophene · Triamteren · Diurene
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
Tell us the grade, the quantity and the market.
Send the molecule or ingredient, the specification and the destination. We reply from Tehran with the questions, the documents and the next step.