API reference

Trifarotene

CAS number
895542-09-3
Molecular formula
C29H33NO4
Molecular weight
459.6 g/mol
Trifarotene — 2D structure
2D structure (PubChem)

About this molecule

Trifarotene is a topical retinoid cream used in the treatment of acne vulgaris that was first approved for use in the United States in October 2019. Retinoids are a class of medications structurally and functionally analogous to [vitamin A], though later generation retinoids such as trifarotene and [adapalene] bear little structural resemblance to vitamin A and are analogous only in function. Trifarotene is considered the first of the "fourth-generation" retinoids due to its uniquely selective activity - this selectivity appears to confer improved efficacy and reduced side effects as compared to older, less selective retinoids.

Source: DrugBank, via PubChem.

Identifiers

IUPAC name
4-[3-(3-tert-butyl-4-pyrrolidin-1-ylphenyl)-4-(2-hydroxyethoxy)phenyl]benzoic acid
InChIKey
MFBCDACCJCDGBA-UHFFFAOYSA-N
SMILES
CC(C)(C)C1=C(C=CC(=C1)C2=C(C=CC(=C2)C3=CC=C(C=C3)C(=O)O)OCCO)N4CCCC4
PubChem CID
11518241

Also known as

Trifarotene · Aklief · trifaroteno · trifarotenum · D10AD06 · Qufarotine · Trofarotene. · Aklief (TN)

Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.

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