API reference
Trihexyphenidyl
- CAS number
- 144-11-6
- Molecular formula
- C20H31NO
- Molecular weight
- 301.5 g/mol
About this molecule
Trihexyphenidyl is only found in individuals that have used or taken this drug. It is one of the centrally acting muscarinic antagonists used for treatment of parkinsonian disorders and drug-induced extrapyramidal movement disorders and as an antispasmodic. Trihexyphenidyl is a selective M1 muscarinic acetylcholine receptor antagonist. It is able to discriminate between the M1 (cortical or neuronal) and the peripheral muscarinic subtypes (cardiac and glandular). Trihexyphenidyl partially blocks cholinergic activity in the CNS, which is responsible for the symptoms of Parkinson's disease. It is also thought to increase the availability of dopamine, a brain chemical that is critical in the initiation and smooth control of voluntary muscle movement.
Source: Toxin and Toxin Target Database (T3DB), via PubChem.
Identifiers
- IUPAC name
- 1-cyclohexyl-1-phenyl-3-piperidin-1-ylpropan-1-ol
- InChIKey
- HWHLPVGTWGOCJO-UHFFFAOYSA-N
- SMILES
- C1CCC(CC1)C(CCN2CCCCC2)(C3=CC=CC=C3)O
- PubChem CID
- 5572
Also known as
trihexyphenidyl · Benzhexol · Triphenidyl · Trihexyphenidyle · Benzhexolum · Trihexifenidilo · Trihexyphenidylum · Apo-Trihex
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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