API reference
Upadacitinib
- CAS number
- 1310726-60-3
- Molecular formula
- C17H19F3N6O
- Molecular weight
- 380.4 g/mol
About this molecule
Upadacitinib is an oral selective inhibitor of Janus associated kinase 1 (JAK-1) that is used in the therapy of moderate-to-severe rheumatoid arthritis. Upadacitinib has been associated with a low rate of serum enzyme elevations during therapy, but has not been linked to cases of clinically apparent acute liver injury although it may pose a risk for reactivation of hepatitis B in susceptible patients.
Source: LiverTox, via PubChem.
Identifiers
- IUPAC name
- (3S,4R)-3-ethyl-4-(1,5,7,10-tetrazatricyclo[7.3.0.02,6]dodeca-2(6),3,7,9,11-pentaen-12-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide
- InChIKey
- WYQFJHHDOKWSHR-MNOVXSKESA-N
- SMILES
- CC[C@@H]1CN(C[C@@H]1C2=CN=C3N2C4=C(NC=C4)N=C3)C(=O)NCC(F)(F)F
- PubChem CID
- 58557659
Also known as
Upadacitinib · ABT-494 · Upadacitinib anhydrous · upadacitinibum · L04AA44 · Rinvoq · ABT 494 · ABBV-599 COMPONENT UPADACITINIB
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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