API reference
Ursodeoxycholic acid
- CAS number
- 128-13-2
- Molecular formula
- C24H40O4
- Molecular weight
- 392.6 g/mol
About this molecule
Ursodeoxycholic acid (UDCA), also known as ursodiol, is a naturally-occurring bile acid that constitutes a minor fraction of the human bile acid pool. UDCA has been used to treat liver disease for decades: its first use in traditional medicine dates back more than a hundred years. UDCA was first characterized in the bile of the Chinese black bear and is formed by 7b-epimerization of [chenodeoxycholic acid], which is a primary bile acid. Due to its hydrophilicity, UDCA is less toxic than [cholic acid] or [chenodeoxycholic acid]. UDCA was first approved by the FDA in 1987 for dissolution of gallstones and for primary biliary cirrhosis in 1996. UDCA works by replacing the hydrophobic or more toxic bile acids from the bile acid pool.
Source: DrugBank, via PubChem.
Identifiers
- IUPAC name
- (4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
- InChIKey
- RUDATBOHQWOJDD-UZVSRGJWSA-N
- SMILES
- C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C
- Other CAS numbers recorded
- 108609-27-4
- PubChem CID
- 31401
Also known as
URSODEOXYCHOLIC ACID · ursodiol · UDCA · Actigall · Ursodesoxycholic acid · Urso Forte · Deursil · 3alpha,7beta-Dihydroxy-5beta-cholan-24-oic acid
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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