API reference
Valproic acid
- CAS number
- 99-66-1
- Molecular formula
- C8H16O2
- Molecular weight
- 144.21 g/mol
About this molecule
Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in 1881 by Beverly S. Burton. It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century. In 1963, a serendipitous discovery was made by George Carraz during his investigations into the anticonvulsant effects of khelline when he found that all of his samples, dissolved in valproic acid, exerted a similar degree of anticonvulsive activity. It first received approval on February 28, 1978 from the FDA under the trade name Depakene. Since then, it has been investigated for neuroprotective, anti-manic, and anti-migraine effects. It is currently a compound of interest in the field of oncology for its anti-proliferative effects and is the subject of many clinical trials in a variety of cancer types.
Source: DrugBank, via PubChem.
Identifiers
- IUPAC name
- 2-propylpentanoic acid
- InChIKey
- NIJJYAXOARWZEE-UHFFFAOYSA-N
- SMILES
- CCCC(CCC)C(=O)O
- PubChem CID
- 3121
Also known as
VALPROIC ACID · 2-Propylpentanoic acid · 2-Propylvaleric acid · Dipropylacetic acid · Depakene · Depakine · Mylproin · Di-n-propylacetic acid
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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