API reference
Valsartan
- CAS number
- 137862-53-4
- Molecular formula
- C24H29N5O3
- Molecular weight
- 435.5 g/mol
About this molecule
Valsartan is an orally active nonpeptide triazole-derived antagonist of angiotensin (AT) II with antihypertensive properties. Valsartan selectively and competitively blocks the binding of angiotensin II to the AT1 subtype receptor in vascular smooth muscle and the adrenal gland, preventing AT II-mediated vasoconstriction, aldosterone synthesis and secretion, and renal reabsorption of sodium, and resulting in vasodilation, increased excretion of sodium and water, a reduction in plasma volume, and a reduction in blood pressure.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- (2S)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid
- InChIKey
- ACWBQPMHZXGDFX-QFIPXVFZSA-N
- SMILES
- CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)[C@@H](C(C)C)C(=O)O
- Other CAS numbers recorded
- 137863-60-6
- PubChem CID
- 60846
Also known as
valsartan · Diovan · Prexxartan · N-(p-(o-1H-Tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-valine · DAFIRO COMPONENT VALSARTAN · COPALIA COMPONENT VALSARTAN · EXFORGE COMPONENT VALSARTAN · IMPRIDA COMPONENT VALSARTAN
Related entries in the range
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