API reference
VERAPAMIL HCl
- CAS number
- 152-11-4
- Molecular formula
- C27H39ClN2O4
- Molecular weight
- 491.1 g/mol
About this molecule
Verapamil Hydrochloride is the hydrochloride form of Verapamil, which is a phenylalkylamine calcium channel blocking agent. Verapamil inhibits the transmembrane influx of extracellular calcium ions into myocardial and vascular smooth muscle cells, causing dilatation of the main coronary and systemic arteries and decreasing myocardial contractility. This agent also inhibits the drug efflux pump P-glycoprotein which is overexpressed in some multi-drug resistant tumors and may improve the efficacy of some antineoplastic agents. (NCI04)
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile;hydrochloride
- InChIKey
- DOQPXTMNIUCOSY-UHFFFAOYSA-N
- SMILES
- CC(C)C(CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC.Cl
- Other CAS numbers recorded
- 23313-68-0
- PubChem CID
- 62969
Also known as
Verapamil hydrochloride · Verapamil HCl · Verelan · Covera · Isoptin SR · Verelan PM · Calan SR · Verapamili hydrochloridum
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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