API reference
Voriconazole
- CAS number
- 137234-62-9
- Molecular formula
- C16H14F3N5O
- Molecular weight
- 349.31 g/mol
About this molecule
Voriconazole (Vfend, Pfizer) is a triazole antifungal medication used to treat serious fungal infections. It is used to treat invasive fungal infections that are generally seen in patients who are immunocompromised. These include invasive candidiasis, invasive aspergillosis, and emerging fungal infections. The increased affinity of voriconazole for 14-alpha sterol demethylase makes it useful against some [fluconazole]-resistant organisms. Voriconazole was approved by the FDA under the trade name Vfend on May 24, 2002.
Source: DrugBank, via PubChem.
Identifiers
- IUPAC name
- (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol
- InChIKey
- BCEHBSKCWLPMDN-MGPLVRAMSA-N
- SMILES
- C[C@@H](C1=NC=NC=C1F)[C@](CN2C=NC=N2)(C3=C(C=C(C=C3)F)F)O
- Other CAS numbers recorded
- 188416-29-7 · 173967-54-9
- PubChem CID
- 71616
Also known as
Voriconazole · Vfend · Voriconazol · Voriconazolum · UK-109,496 · UK109,496 · J02AC03 · 629-701-5
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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