API reference

Warfarin sodium

CAS number
129-06-6
Molecular formula
C19H15NaO4
Molecular weight
330.3 g/mol
Warfarin sodium — 2D structure
2D structure (PubChem)

About this molecule

Warfarin Sodium is the sodium salt form of warfarin, a coumarin and a vitamin K antagonist, with anticoagulant activity. Warfarin sodium inhibits both vitamin K and vitamin K epoxide reductases, thereby interfering with the cyclic interconversion of vitamin K epoxide to its reduced form, vitamin KH2. Vitamin KH2 is a cofactor for the carboxylation of glutamate residues on the N-terminal regions of vitamin K-dependent proteins. As a result, maturation of vitamin K-dependent coagulation factors II, VII, IX, and X and anticoagulant proteins C and S is inhibited. Without these coagulation factors, thrombogenesis and blood clot formation are prevented.

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
sodium 2-oxo-3-(3-oxo-1-phenylbutyl)chromen-4-olate
InChIKey
KYITYFHKDODNCQ-UHFFFAOYSA-M
SMILES
CC(=O)CC(C1=CC=CC=C1)C2=C(C3=CC=CC=C3OC2=O)[O-].[Na+]
Other CAS numbers recorded
5543-79-3 · 67430-45-9
PubChem CID
16204922

Also known as

Warfarin sodium · Sodium warfarin · Aldocumar · Jantoven · Marevan · Prothromadin · Tintorane · Warcoumin

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