API reference

Zanamivir

CAS number
139110-80-8
Molecular formula
C12H20N4O7
Molecular weight
332.31 g/mol
Zanamivir — 2D structure
2D structure (PubChem)

About this molecule

Zanamivir is a sialic acid-analogue neuraminidase inhibitor with antiviral activity. Administered into the respiratory tract by aerosol inhalation, zanamivir selectively binds to and inhibits influenza A and B virus neuraminidase-mediated cleavage of sialic acid residues in host cell membrane-bound glycoprotein receptors for influenza viruses, preventing the release of progeny viruses from host cell surfaces and, so, further viral replication.

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
(2R,3R,4S)-3-acetamido-4-(diaminomethylideneamino)-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid
InChIKey
ARAIBEBZBOPLMB-UFGQHTETSA-N
SMILES
CC(=O)N[C@@H]1[C@H](C=C(O[C@H]1[C@@H]([C@@H](CO)O)O)C(=O)O)N=C(N)N
Other CAS numbers recorded
551942-41-7
PubChem CID
60855

Also known as

zanamivir · Relenza · GANA · 4-Guanidino-Neu5Ac2en · GG167 · GG-167 · GANA (inhibitor) · GG 167

Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.

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