API reference
Zolmitriptan
- CAS number
- 139264-17-8
- Molecular formula
- C16H21N3O2
- Molecular weight
- 287.36 g/mol
About this molecule
Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)1B/1D/(1F) receptor agonists used to treat acute migraine. [Sumatriptan] was the first triptan to be developed, but had poor oral bioavailability and lipophilicity. This led to the development of second-generation triptans, including [almotriptan], [eletriptan], [frovatriptan], [naratriptan], [rizatriptan], and zolmitriptan. Triptans can be administered alone or in combination with an NSAID like [naproxen], and represent the current "gold standard" for acute migraine treatment. Zolmitriptan was first approved by the FDA for sale by Zeneca Pharmaceuticals under the trade name Zomig® on November 25, 1997. It is currently available in both tablet and nasal spray forms.
Source: DrugBank, via PubChem.
Identifiers
- IUPAC name
- (4S)-4-[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]-1,3-oxazolidin-2-one
- InChIKey
- ULSDMUVEXKOYBU-ZDUSSCGKSA-N
- SMILES
- CN(C)CCC1=CNC2=C1C=C(C=C2)C[C@H]3COC(=O)N3
- Other CAS numbers recorded
- 139264-25-8
- PubChem CID
- 60857
Also known as
zolmitriptan · Zomig · Zomigoro · Zomig-ZMT · 311C90 · zolmitriptanum · AscoTop · Cvt-427
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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