Finished product reference
Amphotericin B Nanoliposomal
Gel · Topical · 0.4 % · 15 g
- List code
- 22891
- Pharmacologic class
- Topical polyene antifungal / antileishmanial (nanoliposomal formulation)
What it is and how it works
Amphotericin B binds to ergosterol in the cell membranes of fungi and Leishmania parasites, forming pores that increase permeability and cause cell death. Nanoliposomal encapsulation enhances skin penetration and local delivery while limiting irritation and systemic exposure.
Indications
Topical treatment of cutaneous leishmaniasis; used in some settings for superficial cutaneous fungal infections.
Dosage and administration (summary)
Applied as a thin layer to the lesion, usually twice daily, for the duration specified by the treating physician or protocol.
Contraindications
Hypersensitivity to amphotericin B or excipients.
Warnings and precautions
Local irritation, erythema or itching may occur. For external use only; avoid contact with eyes and mucous membranes. Lesions that are extensive, on the face near the eyes or not responding to treatment should be referred for systemic or alternative therapy.
Storage and supply
Store at 2–8 °C refrigerated; do not freeze.
Source: reference summary prepared from the EU SmPC/EPAR, BNF and WHO Model Formulary. The approved product information in Iran governs.
Reference information for professional sourcing and registration enquiries, not medical advice or a promotion. Drug information is condensed from US FDA prescribing information (public domain, via openFDA and DailyMed) and does not replace the product’s approved labelling in Iran. Availability, origin and documentation are confirmed per enquiry.
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