Finished product reference
Calcipotriol
Ointment · Topical · 50 µg/1g · 30 g
- List code
- 192
- Pharmacologic class
- Topical antipsoriatic; vitamin D3 analogue
What it is and how it works
Calcipotriol binds to the vitamin D receptor in keratinocytes, inhibiting their proliferation and inducing normal differentiation, and modulates local immune responses. It has much less effect on calcium metabolism than calcitriol.
Indications
Topical treatment of mild to moderate plaque psoriasis.
Dosage and administration (summary)
Ointment 50 micrograms/g: apply once or twice daily to affected areas. Maximum 100 g weekly in adults (lower limits in children); treated area should not exceed about 30% of body surface.
Contraindications
Disorders of calcium metabolism; hypercalcaemia; severe renal or hepatic impairment; hypersensitivity to calcipotriol.
Warnings and precautions
Hypercalcaemia may occur if the maximum weekly dose is exceeded or with extensive use; monitor calcium in at-risk patients. Local irritation, burning and dermatitis are common; avoid the face and wash hands after application. Avoid excessive sunlight or UV exposure.
Pregnancy
Use in pregnancy only if clearly necessary, as safety has not been established.
Storage and supply
Store below 25 °C; do not freeze.
Source: reference summary prepared from the EU SmPC/EPAR, BNF and WHO Model Formulary. The approved product information in Iran governs.
Reference information for professional sourcing and registration enquiries, not medical advice or a promotion. Drug information is condensed from US FDA prescribing information (public domain, via openFDA and DailyMed) and does not replace the product’s approved labelling in Iran. Availability, origin and documentation are confirmed per enquiry.
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