Finished product reference
Isoxsuprine Hydrochloride
Tablet · Oral · 10 mg
- List code
- 721
- Pharmacologic class
- Peripheral vasodilator (beta-adrenoceptor agonist)
What it is and how it works
Isoxsuprine is a beta-adrenoceptor agonist with direct relaxant effects on vascular and uterine smooth muscle. It causes peripheral vasodilatation, particularly in skeletal muscle vessels, and inhibits uterine contractility.
Indications
Adjunctive symptomatic treatment of peripheral vascular disease (e.g. arteriosclerosis obliterans, Raynaud’s disease) and cerebrovascular insufficiency; efficacy is not well established and use for preterm labour is no longer recommended.
Dosage and administration (summary)
Adults: 10–20 mg orally 3–4 times daily.
Contraindications
Recent arterial haemorrhage; immediately post-partum; hypersensitivity.
Warnings and precautions
May cause hypotension, tachycardia, palpitations, dizziness, flushing and gastrointestinal upset; rash may require discontinuation. Use with caution in patients with cardiovascular disease, angina or bleeding disorders.
Pregnancy
Not recommended in pregnancy; use for tocolysis has been associated with maternal and neonatal adverse effects.
Storage and supply
Store below 25 °C, protected from moisture.
Source: reference summary prepared from the EU SmPC/EPAR, BNF and WHO Model Formulary. The approved product information in Iran governs.
Reference information for professional sourcing and registration enquiries, not medical advice or a promotion. Drug information is condensed from US FDA prescribing information (public domain, via openFDA and DailyMed) and does not replace the product’s approved labelling in Iran. Availability, origin and documentation are confirmed per enquiry.
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