Finished product reference
Thallium (Sup201/Suptl) Chloride
Injection · Intravenous · 10 mCi
- List code
- 51142
- Pharmacologic class
- Diagnostic radiopharmaceutical (201Tl thallous chloride); myocardial perfusion agent
What it is and how it works
Thallium-201 is a cyclotron-produced radionuclide (physical half-life about 73 hours) that emits mercury X-rays and gamma photons. As a potassium analogue it is actively taken up by viable myocardial cells via Na+/K+-ATPase in proportion to regional blood flow, then redistributes over several hours, allowing differentiation of ischaemic from infarcted myocardium.
Indications
Myocardial perfusion scintigraphy at stress and rest (including redistribution and viability studies) in coronary artery disease; parathyroid and some tumour imaging in selected centres.
Dosage and administration (summary)
Activity and imaging protocol are individualised by the nuclear medicine specialist according to local protocols.
Contraindications
Hypersensitivity to the product; contraindications to the stress agent or exercise testing also apply.
Warnings and precautions
Stress testing requires resuscitation facilities. Radiation dose is higher than with technetium-based agents, so the examination must be clearly justified. Breast-feeding should be interrupted for a prolonged period after administration.
Pregnancy
Use only when clearly necessary, as thallium crosses the placenta and the radiation dose is relatively high.
Storage and supply
Store below 25 °C in lead shielding; use before the expiry time stated on the label.
Source: reference summary prepared from the EU SmPC/EPAR, BNF and WHO Model Formulary. The approved product information in Iran governs.
Other presentations of the same active ingredient
Reference information for professional sourcing and registration enquiries, not medical advice or a promotion. Drug information is condensed from US FDA prescribing information (public domain, via openFDA and DailyMed) and does not replace the product’s approved labelling in Iran. Availability, origin and documentation are confirmed per enquiry.
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