Finished product reference
Tolnaftate
Solution · Topical · 1 % · 10 mL
- List code
- 1236
- Pharmacologic class
- Topical antifungal (thiocarbamate)
What it is and how it works
Tolnaftate inhibits squalene epoxidase in the fungal ergosterol biosynthesis pathway, leading to ergosterol deficiency and accumulation of squalene in the fungal cell. It is active against dermatophytes (Trichophyton, Microsporum, Epidermophyton) and Malassezia furfur, but not against Candida species or bacteria.
Indications
Superficial dermatophyte infections of the skin such as tinea pedis, tinea cruris and tinea corporis; pityriasis versicolor; prevention of recurrent tinea pedis.
Dosage and administration (summary)
Apply a thin layer of the 1% solution to the affected area twice daily, usually for 2–6 weeks and continuing for a short period after symptoms resolve.
Contraindications
Hypersensitivity to tolnaftate or excipients.
Warnings and precautions
For external use only; avoid contact with eyes and mucous membranes. Not effective for nail or scalp infections or for candidiasis. Discontinue if irritation or sensitisation occurs, and reassess if no improvement after about 4 weeks.
Storage and supply
Store below 25 °C; keep the container tightly closed.
Source: reference summary prepared from the EU SmPC/EPAR, BNF and WHO Model Formulary. The approved product information in Iran governs.
Reference information for professional sourcing and registration enquiries, not medical advice or a promotion. Drug information is condensed from US FDA prescribing information (public domain, via openFDA and DailyMed) and does not replace the product’s approved labelling in Iran. Availability, origin and documentation are confirmed per enquiry.
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