API reference
Cefepime
- CAS number
- 88040-23-7
- Molecular formula
- C19H24N6O5S2
- Molecular weight
- 480.6 g/mol

About this molecule
Cefepime is a semisynthetic, broad-spectrum, fourth-generation cephalosporin with antibacterial activity. Cefepime binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(1-methylpyrrolidin-1-ium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
- InChIKey
- HVFLCNVBZFFHBT-ZKDACBOMSA-N
- SMILES
- C[N+]1(CCCC1)CC2=C(N3[C@@H]([C@@H](C3=O)NC(=O)/C(=N\OC)/C4=CSC(=N4)N)SC2)C(=O)[O-]
- PubChem CID
- 5479537
Also known as
cefepime · Cefepima · Cefepimum · CFPM · Renapime · cefepim · J01DE01 · J01DA24
Related entries in the range
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