API reference
CEFEPIME HCl
- CAS number
- 123171-59-5
- Molecular formula
- C19H28Cl2N6O6S2
- Molecular weight
- 571.5 g/mol
About this molecule
Cefepime Hydrochloride is the hydrochloride salt of a semi-synthetic, beta-lactamase-resistant, fourth-generation cephalosporin antibiotic derived from an Acremonium fungal species with broad-spectrum bactericidal activity. Administered parenterally, cefepime inhibits bacterial cell wall synthesis by binding to and inactivating penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity, resulting in a reduction of bacterial cell wall stability and cell lysis. This agent is more active against a variety of Gram-positive pathogens compared to third-generation cephalosporins.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(1-methylpyrrolidin-1-ium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;chloride;hydrate;hydrochloride
- InChIKey
- LRAJHPGSGBRUJN-OMIVUECESA-N
- SMILES
- C[N+]1(CCCC1)CC2=C(N3[C@@H]([C@@H](C3=O)NC(=O)/C(=N\OC)/C4=CSC(=N4)N)SC2)C(=O)O.O.Cl.[Cl-]
- PubChem CID
- 9571075
Also known as
Cefepime hydrochloride · cefepime dihydrochloride monohydrate · Cefepime HCl · Cefepime dihydrochloride hydrate · Cefepime hydrochloride monohydrate · Cefepime In Plastic Container · Cefepime (as hydrochloride) · Cefepime Hydrochloride and Dextrose
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