API reference
Fluconazole
- CAS number
- 86386-73-4
- Molecular formula
- C13H12F2N6O
- Molecular weight
- 306.27 g/mol
About this molecule
Fluconazole is only found in individuals that have used or taken this drug. It is a triazole antifungal agent that is used to treat oropharyngeal candidiasis and cryptococcal meningitis in AIDS. Fluconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary to convert lanosterol to ergosterol. As ergosterol is an essential component of the fungal cell membrane, inhibition of its synthesis results in increased cellular permeability causing leakage of cellular contents. Fluconazole may also inhibit endogenous respiration, interact with membrane phospholipids, inhibit the transformation of yeasts to mycelial forms, inhibit purine uptake, and impair triglyceride and/or phospholipid biosynthesis.
Source: Toxin and Toxin Target Database (T3DB), via PubChem.
Identifiers
- IUPAC name
- 2-(2,4-difluorophenyl)-1,3-bis(1,2,4-triazol-1-yl)propan-2-ol
- InChIKey
- RFHAOTPXVQNOHP-UHFFFAOYSA-N
- SMILES
- C1=CC(=C(C=C1F)F)C(CN2C=NC=N2)(CN3C=NC=N3)O
- Other CAS numbers recorded
- 123631-92-5
- PubChem CID
- 3365
Also known as
fluconazole · Diflucan · Triflucan · Biozolene · Elazor · Fluconazol · Zoltec · Flucostat
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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