API reference
Melphalan
- CAS number
- 148-82-3
- Molecular formula
- C13H18Cl2N2O2
- Molecular weight
- 305.2 g/mol
About this molecule
Melphalan is an orally and parenterally administered nitrogen mustard-like alkylating agent used in the therapy of multiple myeloma and ovarian cancer. Melphalan therapy has been associated with low rates of serum enzyme elevations during therapy, but when used in high doses as myeloablative therapy in preparation for hematopoietic cell transplantation, it is associated with high rates of enzyme elevations and acute liver injury due to sinusoidal obstruction syndrome.
Source: LiverTox, via PubChem.
Identifiers
- IUPAC name
- (2S)-2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoic acid
- InChIKey
- SGDBTWWWUNNDEQ-LBPRGKRZSA-N
- SMILES
- C1=CC(=CC=C1C[C@@H](C(=O)O)N)N(CCCl)CCCl
- Other CAS numbers recorded
- 8057-25-8
- PubChem CID
- 460612
Also known as
melphalan · Melfalan · L-Sarcolysine · L-PAM · Phenylalanine mustard · L-Phenylalanine mustard · L-Sarcolysin · Levofalan
Related entries in the range
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