API reference
MELPHALAN HCl
- CAS number
- 3223-07-2
- Molecular formula
- C13H19Cl3N2O2
- Molecular weight
- 341.7 g/mol
About this molecule
Melphalan Hydrochloride is a bifunctional alkylating agent and phenylalanine derivative of nitrogen mustard. Melphalan hydrochloride is converted into highly reactive ethylenimmonium intermediates that induce covalent guanine N7-N7 intra- and inter-crosslinks and alkylation of adenine N3 of DNA. This agent also alkylates RNA and protein structures. As a result RNA transcription and protein synthesis are inhibited, ultimately leading to cell growth arrest and/or death.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- (2S)-2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoic acid;hydrochloride
- InChIKey
- OUUYBRCCFUEMLH-YDALLXLXSA-N
- SMILES
- C1=CC(=CC=C1C[C@@H](C(=O)O)N)N(CCCl)CCCl.Cl
- PubChem CID
- 9927978
Also known as
Melphalan hydrochloride · Melphalan HCl · Alkeran hydrochloride · Evomela · L-Sarcolysine hydrochloride · Phenylalanine mustard hydrochloride · Melfalan hydrochloride · Sarcolysin hydrochloride, l-
Related entries in the range
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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