API reference
Methylprednisolone
- CAS number
- 83-43-2
- Molecular formula
- C22H30O5
- Molecular weight
- 374.5 g/mol
About this molecule
Methylprednisolone is a [prednisolone] derivative glucocorticoid with higher potency than [prednisone]. It was first described in the literature in the late 1950s. Methylprednisolone was granted FDA approval on 24 October 1957. In the outbreak of COVID-19, low dose methylprednisolone-based therapy was successful in treating COVID-19-associated pneumonia in one patient with long-term immunosuppression. The efficacy of methylprednisolone in novel coronavirus pneumonia is being investigated further in clinical trials.
Source: DrugBank, via PubChem.
Identifiers
- IUPAC name
- (6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
- InChIKey
- VHRSUDSXCMQTMA-PJHHCJLFSA-N
- SMILES
- C[C@H]1C[C@H]2[C@@H]3CC[C@@]([C@]3(C[C@@H]([C@@H]2[C@@]4(C1=CC(=O)C=C4)C)O)C)(C(=O)CO)O
- PubChem CID
- 6741
Also known as
methylprednisolone · Medrate · Medrone · Urbason · 6alpha-Methylprednisolone · Metilbetasone · Promacortine · Metastab
Related entries in the range
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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