API reference
QUINAPRIL HCl
- CAS number
- 82586-55-8
- Molecular formula
- C25H31ClN2O5
- Molecular weight
- 475 g/mol
About this molecule
Quinapril Hydrochloride is the hydrochloride salt form of quinapril, a prodrug and non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Quinapril is hydrolized into its active form quinaprilat, which binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This abolishes the potent vasoconstrictive actions of angiotensin II and leads to vasodilatation. Quinapril also causes a decrease in angiotensin II-induced aldosterone secretion by the adrenal cortex, thereby promoting diuresis and natriuresis, and increases bradykinin levels.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- (3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxylic acid;hydrochloride
- InChIKey
- IBBLRJGOOANPTQ-JKVLGAQCSA-N
- SMILES
- CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N2CC3=CC=CC=C3C[C@H]2C(=O)O.Cl
- PubChem CID
- 54891
Also known as
QUINAPRIL HYDROCHLORIDE · QUINAPRIL HCL · Korec · Accuprin · Quinazil · Acequin · Acuitel · Hemokvin
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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